Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31fb964e2148aff14f5bfc5f5ae6fbaf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
filingDate |
2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfde86c2fa80b8ca42d5a2c67981030c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_191f3193872dbe8a93419e2737f20c0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8844e40b762a763ee1ceeeeefbefd06d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51cdd029724e26adbe6f4472d7ed28fe |
publicationDate |
2012-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2451963-A1 |
titleOfInvention |
Method of increasing the expression yield of vitamin k-dependent proteins |
abstract |
The invention encompasses the use of one or more compounds selected from a list comprising i) reduced forms of vitamin K and/or ii) reduced forms of a vitamin K analog and/or iii) reduced forms of a vitamin K precursor for the expression of one or more functional vitamin K-dependent proteins in cell culture as well as processes for the fermentation of eucaryotic cells expressing one or more vitamin K-dependent proteins wherein one or more compounds selected from a list comprising i) reduced forms of vitamin K and/or ii) reduced forms of a vitamin K analog and/or iii) reduced forms of a vitamin K precursor are added to the cell culture medium before and/or during the fermentation process. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844345-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11286292-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267869-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015158696-A1 |
priorityDate |
2009-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |