Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9871e02d1c09cc338f51aecbb5510178 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-12 |
filingDate |
2006-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0b37fe6f2f2e083699b0e43faeecfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0249bb7bb3ad75cf0ee68bd4ec084c24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dfd2971a033674eb1bea2548b7476aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3bce4bfae35001b1ece730858d07436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ac684f0116582fb83a65b70075a6d72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f6e866fb8885de4c638d1f5cda95ddb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a72007460dee73ba057b03278d405ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b418001b1f271217868cdc1f62ea4ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5980daa61dc85465e9ff4fe2f6a84620 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7768aed80d8803613c12a7fb42d54a7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571e7332c93cfb2349fd28af50053a87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69da3460a949c82005aa1f01403c1844 |
publicationDate |
2012-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2447283-A2 |
titleOfInvention |
Human monoclonal antibodies to activin receptor-like kinase-1 (ALK-1) |
abstract |
The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to the extracellular doman (ECD) of activin receptor-like kinase-1 (ALK-1) and that function to abrogate the ALK-1/TGF-beta-1/Smad1 signaling pathway. The invention also relates to heavy and light chain immunoglobulins derived from human anti-ALK-1 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of makind human anti-ALK-1 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention. |
priorityDate |
2005-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |