Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1966f3c715acc0fa006db05d916301a7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 |
filingDate |
2010-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e4759f2187ac24b6965f084d31c03d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ce78406db79959f87d2555e813c4e16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a0b83253ec77ad7653cbc66dac1e8a7 |
publicationDate |
2012-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2441771-A1 |
titleOfInvention |
New 12alpha-hydroxysteroid dehydrogenase mutants, method for their manufacture and application thereof |
abstract |
The present invention relates to novel 12α-hydroxysteroid dehydrogenase mutants, nucleic acid sequences, expression cassettes and vectors coding therefor; recombinant microorganisms containing corresponding coding nucleic acid sequences; Process for the preparation of such 12 α-hydroxysteroid dehydrogenase mutants; Process for the enzymatic oxidation of 12α-hydroxysteroids using such mutants, process for the enzymatic reduction of 12-keto steroids using such enzymes; Method for the qualitative or quantitative determination of 12-ketosteroids or 12α-hydroxysteroids using the 12α-hydroxysteroid dehydrogenase mutants according to the invention; and a method of producing ursodeoxycholic acid comprising enzyme-catalyzed cholic acid oxidation using the 12α-hydroxysteroid dehydrogenase mutants of the present invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014032777-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113061637-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102012017026-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114134067-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112080479-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116497082-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116497082-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115786292-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115786292-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111593085-A |
priorityDate |
2010-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |