http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2441769-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7f871411f032ed0fb0e077a4ae2816f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 |
| filingDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eebcc71cc31abdf77790d44bc5d6180 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cafa2916cf11cdcce4c1352140bd029a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4059b77f4d96c07ba6de095c80df5f59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_453f6c77c29fd823179dcb03c4305629 |
| publicationDate | 2012-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2441769-A1 |
| titleOfInvention | Design, synthesis and assembly of synthetic nucleic acids |
| abstract | Methods of synthesizing oligonucleotides with high coupling efficiency (>99.5%) are provided. Methods for purification of synthetic oligonucleotides are also provided. Instrumentation configurations for oligonucleotide synthesis are also provided. Methods of designing and synthesizing polynucleotides are also provided. Polynucleotide design is optimized for subsequent assembly from shorter oligonucleotides. Modifications of phosphoramidite chemistry to improve the subsequent assembly of polynucleotides are provided. The design process also incorporates codon biases into polynucleotides that favor expression in defined hosts. Design and assembly methods are also provided for the efficient synthesis of sets of polynucleotide variants. Software to automate the design and assembly process is also provided. |
| priorityDate | 2004-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1302.