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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2124ebe02ffce34f20b6f58c86c027b
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publicationDate 2012-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2414380-A2
titleOfInvention Method for purifying recombinant fsh
abstract The present invention relates to a method for purifying a recombinant follicle stimulating hormone (FSH) or recombinant FSH variant. The method comprises the steps of subjecting a liquid containing a recombinant FSH or recombinant FSH variant to an anion exchange chromatography, to a hydrophobic interaction chromatography, and to a dye affinity chromatography, wherein these chromatographies may be performed in any order, and wherein the method neither comprises a weak anion exchange chromatography nor a reverse phase chromatography. The method of purification results in a high yield of recombinant FSH having a desired degree of purity. The obtained FSH is especially useful for the prophylaxis and treatment of disorders and medical indications where FSH preparations are considered as useful remedies.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014159813-A1
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