http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2412295-A1

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publicationDate 2012-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2412295-A1
titleOfInvention Fluorescence observation device, fluorescence observation system, and fluorescence image processing method
abstract Observation is performed with a fluorescence image having high quantitativeness by satisfactorily eliminating dependencies on distance and angle that remain in an image that has been subjected to division. Provided is a fluoroscopy apparatus (1) including an illumination portion (4) provided with a light source (3) that radiates illumination light and excitation light; a fluorescence imaging unit (18) that acquires a fluorescence image by imaging fluorescence generated at an subject (X); a return-light imaging unit (17) that acquires a reference image by imagine return light returning from the subject (X); and an image-correcting unit (6) that corrects the fluorescence image imaged by the fluorescence imaging unit (18) by using the reference image imaged by the return-light imaging unit (17), wherein the image-correcting unit (6) performs the following processing: FL revice = A × FL before x / B × RL before y , nwhere FL revice is a luminance value of a corrected fluorescence image, FL before and RL before are luminance values of acquired fluorescence image and reference image, A and B are constants, and x and y are exponents for staying within a permissible error.
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