Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bd7a45a343acd10e3f5d8775dda2157 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H11-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
filingDate |
2010-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87b7dc0d25b64ef1cd178c72e000a77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62bf4655e133fd8ccd2cbc8e5bc57b2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d0c1dbc572615ee78bd57814e84a47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1656865a38c730ff3b94c1c2ef1ba556 |
publicationDate |
2012-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2411528-A1 |
titleOfInvention |
Alpha-selective sialyl phosphate donors for preparation of sialosides and sialoside arrays for influenza virus detection |
abstract |
A novel N-acetyl-5- N ,4- O -carbonyl-protected dibutyl sialyl phosphate donor for sialylation of both primary and sterically hindered secondary acceptors to prepare sialosides with high yield and α-selectivity is disclosed. Methods for making disaccharide building blocks comprising α(2→3), α(2→6), α(2→8), α(2→8)/α(2→9) alternate, and α(2→9) sialosides are provided. methods for one-pot synthesis of complex sialosides are disclosed. Libraries of sialosides and methods for using the libraries for detection and receptor binding analysis of surface glycoproteins or pathogens and cancer cells are disclosed. Methods for distinguishing between hemagglutanin (HA) from various strains of influenza are provided. |
priorityDate |
2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |