| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5943d18ba69fd6d98c2aee04d524769 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0402 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
| filingDate |
2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94fe1af1b604535c50fdb6f0972759df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa0bcc530b71a5a2c2625236915be595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c02f0a5dae33f0446fd34615534c54fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f4f25aa21264a48a9593d4adb12e9bd |
| publicationDate |
2012-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2411360-A1 |
| titleOfInvention |
Radiolabeled fluorine derivatives of methionine |
| abstract |
The invention provides compound which is an 18 F-radiolabelled S-propylhomocysteine or a derivative thereof. The compound has an enantiomeric purity of at least about 90%. 18 F- radiolabelled S-propylhomocysteine may be made by treating an N-protected ester of a substituted S-propylhomocysteine with a complexed F" salt in the presence of a base to form a protected product and then deprotecting the protected product to form the 18 F- radiolabelled S-propylhomocysteine. In this method the N-protected ester has a leaving group on the S-propyl group and has an enantiomeric purity of at least about 90%. The base should be such that it does not cause racemisation of the protected product. |
| priorityDate |
2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |