| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2303ecd499f519a25eb572d48d1ca16a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b49b135f099e96a0e4cab2427a48ae8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0752ae37470d38fb00b638f45de8f59 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
| filingDate |
2009-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e2339df51ea878b715996fd2371c12b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e020b674ccc6608cff8c85e71af30847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c583afbf0bd951e9db356c3a6387fc07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f95ee8ba5f3d6434e812d34f76e5054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e8e913cfd851cc0e275f37607e9959 |
| publicationDate |
2012-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2408445-A1 |
| titleOfInvention |
Gold (iii) complexes with oligopeptides functionalized with sulfur donors and use thereof as antitumor agents |
| abstract |
The invention concerns Au(III) complexes of the type [Au III X 2 (Pdtc)] (X = halogen, pseudo-halogen; pdtc = peptide-/esterified peptidedithiocarbamato) which are able to both maintain the antitumor properties and the lack of nephrotoxic side-effects of the previously reported Au(lll)-dithiocarbamato complexes, together with an improved bioavailability through the peptide-mediated cellular internalization. The Au(III) complexes described have shown a significant biological activity on human tumor cell lines and, thus, they can be advantageously used as antineoplastic agents. The preparation method and use for the treatment of tumor pathologies of the Au(III) complexes of the invention are further described. |
| priorityDate |
2009-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |