http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2406375-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_394e1eac0f43a87fa452f9d345ba37b0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2010-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b41c20cf2f0655d3dcb36b000dc452bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3218c2dd4e6657558ddfbe602f465173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c76e70355f06ed1577fe778f3f473365 |
| publicationDate | 2012-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2406375-A1 |
| titleOfInvention | Cell-specifically effective molecules on the basis of sirna and application kits for the production thereof and use thereof |
| abstract | 1. Cell-specifically effective molecules on the basis of siRNA and application kits for the production thereof and use thereof. 2.1. The aim of the invention is to create a link between siRNA and one or more peptides, wherein the siRNA is activated after peptide separation, without the remaining linkers and/or remaining peptide residues significantly impairing the biological efficacy of the siRNA activated in the cell. 2.2. According to the invention, the peptide or peptides (3) are coupled to the SiRNA (2) by way of a special amino Cn linker, for example an amino C6 linker (1), which does not impair or only insignificantly impedes the biological efficacy of the siRNA despite remaining on the SiRNA and despite any peptide residue that may remain. 2.3. Said molecules are used, for example, to influence gene expression or preferably diseased and infected organs or cells or to reduce the expression of desired genes in cell mixtures. |
| priorityDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.