abstract |
A composition for use as a dermal filler, and a method for improving skin imperfections are disclosed, the composition comprising an alloplastic injectable suspension comprising beads based on a biocompatible material and a physiologically acceptable suspending agent, wherein the beads include eukaryotic cells synthesizing and/or secreting one or more constituents of the dermal extracellular matrix, said eukaryotic cells being encapsulated by a sheath of said biocompatible material, and the method comprises intradermal and/or subdermal under-injection of said composition. |