http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2404612-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf59dd243dc4535fc8efd12e0a98a922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0f4d4fba9dd4070b16dbe5df32750bf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2010-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81924124fe66dd32c446e5a516f57de0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c61fd940456ec063fb4d4740edc23891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b1744766badcea449571d05da3cb5f2 |
| publicationDate | 2012-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2404612-A1 |
| titleOfInvention | Diagnosis, prophylaxis and therapy of Alzheimer's disease and other neurodementing disorders |
| abstract | The present invention relates to a polypeptide having an amino acid sequence comprising at least two substitutions of the glycine residues in one or more GXXXG motives in the amino acid sequence of the wild type Aβ peptide as depicted in SEQ ID NO:1. Furthermore the present invention relates to methods and a kit for diagnosing a neurodementing disease. The present invention further relates to the polypeptide for use as a medicament in human and veterinary medicine and as a diagnostic substance, in particular for use as a medicament for the prevention and for the diagnosis of the progression of Alzheimer's disease, Down's syndrome, Dementia with Lewy bodies, fronto-temporal dementia, misfolded protein/peptide related diseases, cerebral amyloid angiopathy, Prion disease and amyloidoses. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109072274-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017179646-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017179646-A1 |
| priorityDate | 2010-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.