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filingDate 2010-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27cd769b6c43f11d1b233c1f38a7656b
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publicationDate 2012-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2402457-A1
titleOfInvention Detecting probes and liquid phase chips for braf gene mutation and detecting methods thereof
abstract Probes, liquid chips and method for detecting BRAF exon 15 mutations are disclosed. The liquid chip for detecting BRAF exon 15 mutations comprises: microspheres coupled with amino-substituted wild-type probes specific for exon 15, and microspheres coupled with amino-substituted mutant-type probes specific for exon 15; primers for amplifying target sequences enriched for mutant alleles of BRAF exons 15 and biotin-labeled at the terminal. The method of this invention is rapid and accurate in detection, and easy in operation, whereby the detection efficiency is greatly improved.
priorityDate 2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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