Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4b95c473e3043530b7da36cf959996c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-12 |
filingDate |
2009-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ef0aa2fb3b19872399008de2a01592d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504bd86ef6c1e13a4aa9313cbe512f99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b83cb9ddbc3c6f4a8b8cff2cf103a683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1574b4c6ded28e47768b824af9c9b914 |
publicationDate |
2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2398823-A1 |
titleOfInvention |
Monoclonal antibodies against vaginolysin |
abstract |
The present invention describes new monoclonal antibodies specific to vaginolysin from Gardnerella vaginalis that neutralize the cytolytic activity of vaginolysin. These antibodies might be useful for diagnostics of Gardnerella vaginalis infection. The present invention describes two new hybridoma cell lines 9B4 and 23A2 that produce neutralizing antibodies against vaginolysin. Monoclonal antibody produced by hybridoma 9B4 has a more potent neutralizing activity than that of hybridoma 23A2. The genetic material from hybridomas 9B4 and 23A2 can be used for developing biopharmaceutical recombinant antibodies with a potential therapeutic use. ˙ |
priorityDate |
2009-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |