Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_960b645e3458a87aef1767f5574b6856 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0eb2fd8bb5535d59d4e15b75290ccc7b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2010-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ff9f9f4eb1003cadcc37510f828ad84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d7568ff0dd89537aabaec2984f826d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c85a79c23d36a3dcaaf474152c653a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7295496377eee2210bb9e7c86c96357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_671bee2bb8d5c7a742abb7637ed9e1cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2c5db7bc715a2b5a00600ebeda566c |
publicationDate |
2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2391639-A1 |
titleOfInvention |
Enzyme mutant |
abstract |
The invention relates to constructs comprising a nucleic acid binding protein and a surface. At least one native accessible cysteine residue is removed from the binding protein. The binding protein is attached to the surface via one or more accessible cysteine residues. The removal of other accessible cysteine residues from the protein allows control attachment to the surface. The constructs can be used to generate transmembrane pores having a nucleic acid binding protein attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect each of its component nucleotides by stochastic sensing. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9678012-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11112361-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10174363-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10371634-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11287382-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10533945-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9945779-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11719635-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11719636-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9983135-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11001875-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11175227-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11181477-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11209363-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9784679-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9606058-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11391626-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10288566-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10288565-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9696258-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9863880-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10502684-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9885657-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9921157-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11428635-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10712273-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10712274-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9759658-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10775305-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10048208-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10845308-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344200-B2 |
priorityDate |
2009-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |