| abstract |
The present invention is concerned with a method for diagnosing whether a subject suffers from a mild or severe form of liver cirrhosis based on determining the amount of GDF-15 (Growth differentiation factor 15), PlGF (Placental Growth Factor), and/or HGF (Hepatocyte Growth Factor) in a sample from said subject and comparing the, thus, determined amount (s) with a reference amount (reference amounts). The method may further comprise determining the amount of adiponectin in a sample from said subject, and comparing said amount to a reference amount for adiponectin. Moreover, the present invention relates to identifying a subject being susceptible to live transplantation comprising determining the amount of GDF-15, PlGF (Placental Growth Factor), bilirubin, and/or HGF (Hepatocyte Growth Factor) in a sample from said subject and comparing the, thus, determined amount (s) with a reference amount (reference amounts). Further encompassed by the present invention are a kit and a device adapted to carry out the method of the present invention. |