| abstract |
The invention relates to polypeptides which enable the specific targeting of a molecule of interest to homeoprotein Otx2 target cells. These polypeptides are defined by the general sequence: B 1 B 2 X 1 B 3 B 4 X 2 B 5 X 3 X 4 X 5 X 6 B 6 X 7 X 8 X 9 (SEQ ID NO: 1), in which: B 1 , B 2 , B 3 , B 4 , B 5 and B 6 are independently arginine or lysine; X 1 and X 8 are independently asparagine or glutamine; X 2 is aspartic acid or glutamic acid; X 3 , X 4 and X 6 are independently threonine or serine; X 5 is phenylalanine, tyrosine or tryptophan; X 7 represents alanine or glycine; X 9 is leucine, isoleucine or valine. |