http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2386857-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd569fbfa1953ca9b7b375510e4d2763 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-40 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2009-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1be7986d333ca288a7f52eecab2236a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef08fa8d08e9a85a7e7cde69b5cec3bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4251124eb7e1ad59cc9d4d7b801a4bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a437e6f4832ff5c2e4be3cbf596f454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aaeb73b2d774141bcbcbb4d1eb24878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4bff23e4e21bbc89b6ef5ef48455870 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c6d1a6fa25d944f09c8f45a02a2130f |
publicationDate | 2011-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2386857-A1 |
titleOfInvention | Method for assaying keratan sulfate, assay kit therefor and method for detecting joint disease by using same |
abstract | The inventions provides a method for immunologically determining a keratan sulfate level which method includes bringing an anti-keratan sulfate monoclonal antibody into contact with a biological sample, the anti-keratan sulfate monoclonal antibody exhibiting a relative reaction specificity between keratan sulfate-I and keratan sulfate-II represented by IC50 KS-I/KS-II of 0.4 to 5, to thereby provide a signal; and detecting keratan sulfate contained in the biological sample from the signal. On the basis of the method, the invention also provides a joint disease detection method and a method for assessing the effect of a remedy for a joint disease and a candidate substance therefor. Through these methods, a very small amount of keratan sulfate contained in a sample, can be determined. Particularly, these methods can determine, at high-sensitivity and high-specificity, the total keratan sulfate including keratan sulfate-I, which have been difficult to determine through a conventional technique. The methods also enables detect a joint disease and assess the effect of a remedy for a joint disease or a candidate substance therefor. |
priorityDate | 2008-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1043.