http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2376218-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e1dfcbdcafbe3a4a72ef04553310205 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-04 |
| filingDate | 2009-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_968cb2f81f1ebecd851eb851091e88ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03868ac0cf466a89063218d853843e22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1bd594aa992612ff5b0acee362c04fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b22f29ad6e174753d38a96e913374c43 |
| publicationDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2376218-A1 |
| titleOfInvention | Method for preparing lipid nanoparticles |
| abstract | The present invention relates to a useful method for preparing nanocapsules with a liquid lipid core and a hard shell and loaded with at least one hydrophilic active agent, said method including at least the steps of: i) using at least one first water-in-oil microemulsion containing, in the hydrophilic phase thereof, at least one hydrophilic active agent; ii) using at least one second microemulsion that is formulated by the phase inversion of an emulsion; iii) adding said first microemulsion into said second microemulsion under conditions that are conducive to the formation of a novel microemulsion architecture wherein said hydrophilic active agent remains present in the hydrophilic phase of the first microemulsion; and iv) quenching the mixture that is formed in the preceding step so as to obtain microcapsules containing said hydrophilic active agent and being made of a lipid core that is liquid at room temperature and coated in a hard film at room temperature. The invention also relates to nanocapsules obtainable by said method. |
| priorityDate | 2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.