http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2376067-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b43df28f012b376838b0fb63dd2fddfc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
filingDate | 2009-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97356507c0a98bf26b861e71d2bc8434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58dad922a7dd60a45caf0a2fd885e2f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_909af7a07c33884f6f4761c4f85c461d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b4a4d89a95b5f9a1b39ab37b2e9f6a6 |
publicationDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2376067-A2 |
titleOfInvention | Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof |
abstract | An improved excipient comprising substantially homogeneous particles of a compressible, high functionality granular microcrystalline cellulose based excipient is provided. The improved excipient comprises microcrystalline cellulose and a binder, and optionally a disintegrant, and is formed by spraying a homogeneous slurry of the components. The excipient provides enhanced flowability/good flow properties, excellent/high compactibility, and increased API loading and blendability as compared to the individual components, and as compared to conventional excipients formed from the same materials. The improved excipient has strong intraparticle bonding bridges between the components, resulting in a unique structural morphology including significant open structures or hollow pores. The presence of these pores provides a surface roughness that is the ideal environment for improved blending with an API. |
priorityDate | 2008-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 322.