Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d9b5e708de663cc48cbd4ae71980b15 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
filingDate |
2009-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac90e3aaea139e93363c16fa97d944a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46bbb591eb51029e80fd8b2ef3427984 |
publicationDate |
2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2370451-A2 |
titleOfInvention |
Method for the synthesis of phosphorus atom modified nucleic acids |
abstract |
Described herein are methods of syntheses of phosphorous atom-modified nucleic acids comprising chiral X-phosphonate moieties. The methods described herein provide backbone-modified nucleic acids in high diasteteomeric purity via an asymmetric reaction of an achiral molecule comprising a chemically stable H -phophonate moiety with a nucleoside/nucleotide. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428019-B2 |
priorityDate |
2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |