abstract |
The present invention provides a therapeutic composition comprising: (i) Trolox, Na + , K + , Ca 2+ , Mg 2+ ' Cl - , H 2 PO 4 n - , HEPES, lactobionate, sucrose, mannitol, glucose, dextran-40, adenosine, glutathione; and (ii) stem cells or progenitor cells, wherein the composition does not comprise a dipolar aprotic solvent, in particular DMSO. The present invention also relates to methods of formulating said composition for cryopreservation and subsequent direct administration to a patient, and medicaments comprising said composition. |