Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 |
filingDate |
2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95548c069546f31c71b6d76b35779a50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba9605d9905404f94869abc35349f39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1de232c0bb3ae40eb65575b8a722ff67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c9cefe56eea430ef9961bbd8bd7c4b |
publicationDate |
2013-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2365974-B1 |
titleOfInvention |
Fluorinated benzothiazole derivatives, preparation method thereof and imaging agent for diagnosing altzheimer's disease using the same |
abstract |
The present invention relates to fluorinated benzothiazole derivatives, a preparation method thereof, and an imaging agent for diagnosing Alzheimer's disease using the same, and more particularly to fluorinated benzothiazole derivatives represented by Chemical Formula 1, derivatives of Chemical Formula 2 as a starting material for preparation thereof, a preparation method thereof, and an imaging agent for diagnosing Alzheimer's disease using fluorinated benzothiazole derivatives with a strong binding force to beta-amyloid plaque, which is a kind of biomarker for Alzheimer's disease. According to the present invention, fluorine-labeled benzothiazole derivatives, which have been difficult to synthesize by conventional methods, may be obtained by simple processes and the thus-obtained benzothiazole derivatives may be useful in diagnosing the presence and severity of Alzheimer's disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11224668-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017151487-A1 |
priorityDate |
2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |