| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad78e8702dfa23ca1a9b9851044b7fcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d67f094b01a4dd0051e0b59b79abd8a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-36 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F16-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09D129-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0442
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F116-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-18 |
| filingDate |
2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0361be6521c0a20f133008771a525df9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ecaa2d5531b48bd5db3a05f343c4f1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c177810129f91f51f05fb75ef35517c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d44dacc4f5439e0e53748f526e5232a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf345a330c4fd7e1d3f5e38da0c53f98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_036eb33fcaff4a7eb0c58e7d0153714e |
| publicationDate |
2011-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2365009-A1 |
| titleOfInvention |
Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof |
| abstract |
The invention concerns a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a PVA having covalently grafted thereon iodinated benzyl groups comprising 1 - 4 iodine atoms per benzyl group, a process for preparing the same comprising reacting a 0 - 100 % hydrolyzed PVA with a iodinated benzyl derivative comprising 1 - 4 iodine atoms per benzyl group in a polar aprotic solvent in the presence of a base in anhydrous conditions. Said iodo-benzylether-PVA is useful as embolic agent in an injectable embolizing composition. The invention also concerns an injectable embolizing composition comprising the iodo-benzylether-PVA and a water-miscible, biocompatible solvent solubilizing the iodo-benzylether-PVA, wherein the concentration of the iodo-benzylether-PVA in the composition is selected in the range of 5 - 65 w/w % so that the composition is capable of forming a cohesive mass upon contact with a body fluid by precipitation of the iodo-benzylether-PVA. Said injectable embolizing composition is particularly useful for forming in-situ a cohesive mass in a blood vessel or into a tumor |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020202210-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11744916-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114262279-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023083102-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017158482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2523863-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2523863-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022183926-A1 |
| priorityDate |
2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |