Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41ca9b060cc324d126a65f7b6f529acc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0065 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
filingDate |
2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bca317879535d45281b93ed72a56a70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8529c889d54f52a96fca7e54c33c3c23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed53f8f955cbfcd117a1b78930dba88d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30ec738f4112621b1d1e89095cbe271b |
publicationDate |
2011-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2361615-A1 |
titleOfInvention |
Dipyridamole prolonged-release tablet |
abstract |
The present invention relates to a gastro-retentive, prolonged-release tablet formulation comprising in the intragranular phase a pharmaceutically active ingredient and a water-swellable polymer, and in the extragranular phase hydroxypropyl methyl cellulose (HPMC). The tablet of the present invention is further characterized in that it contains a gas generating agent, thereby causing the tablet to float on the gastric juice. The tablet is particularly suitable for dipyridamole which is a drug that inhibits thrombus formation. The present invention thus provides an alternative to the commercially available dipyridamole containing pharmaceutical compositions marketed under the tradenames Aggrenox ® and Persantine ® . |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154435-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154435-B |
priorityDate |
2010-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |