| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7450f8b709a8f9c94070d7468a736d31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2009-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae2b47dc446b0f6fd6353f12a2264049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bcef3d318b4463d5b7a7f1329d5fa5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77567aaab46d30e3c895ef61353fca86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1307133d9d0b269c3d3e0250d2807aaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6997ed8465711332c97fc43a1488ae4b |
| publicationDate |
2011-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2361305-A2 |
| titleOfInvention |
Nucleic acid compounds for inhibiting birc5 gene expression and uses thereof |
| abstract |
The present disclosure provides RNA molecules, for example, meroduplex ribonucleic acid molecules (mdRNA), capable of decreasing or silencing BIRC5 gene expression. An mdRNA of this disclosure comprises at least three strands that combine to form at least two non-overlapping double-stranded regions separated by a nick or gap wherein one strand is complementary to a BIRC5 mRNA. Also provided are methods of decreasing expression of a BIRC5 gene in a cell or in a subject to treat a BIRC5-related disease. |
| priorityDate |
2008-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |