| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9a36328274867f46f8fc1fb9c868703 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C61-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-46 |
| filingDate |
2009-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360e4a0dab865fadb4659141e25b2060
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_739236d840bf396a299bb0b59bc2b46d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ae5678b9bccc07f0de9c5fcdad1d700
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8100e030e4b9d1871ac262adbc39a88d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15defe780aecda8c0cd087d95d301844
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7531d2edc6e2728663c217c5ad32a454 |
| publicationDate |
2011-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2358661-A1 |
| titleOfInvention |
Process for the preparation of trans 4-amino-cyclohexyl acetic acid ethyl ester hcl |
| abstract |
The invention relates to a process for the preparation of trans 4-amino-cyclohexil ethyl acetate HCl wherein d) hydrogenating 4-nitrophenyl acetic acid in a protic solvent at a temperature between 40-500C in the presence of Pd/C under 0.1-0.6 bar overpressure, and e) further hydrogenating the 4-aminophenyl acetic acid obtained in situ in step a) at a temperature between 50-60 0C under 1-4 bar overpressures, then f) heating to reflux the 4-aminocyclohexil acetic acid obtained in step b) for 1-3 hours in hydrochloric ethanol, and if desired after removing the solvent acetonitrile was added to the residue obtained and distilled off. |
| priorityDate |
2008-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |