http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2356988-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_241c3d4e236532a2e822eb39f56b1be9 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
filingDate | 2009-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5849d8d4a662339af0e6636d56e82c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59d36cbae48ce16ea3e051fa045c3e77 |
publicationDate | 2011-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2356988-A1 |
titleOfInvention | Therapeutic agent for chorioretinal degenerative diseases comprising pyridine-3-carbaldehyde o-(piperidin-1-yl-propyl)-oxime derivative as active ingredient |
abstract | Provided is a novel prophylactic or therapeutic agent for a chorioretinal degenerative disease. The compound of formula (1) or its salt has inhibitory effects on photoreceptor cell death or visual cell death in a mouse model of light damage. Therefore, the compound or its salt is useful as a prophylactic or therapeutic agent for a chorioretinal degenerative disease such as age-related macular degeneration, retinitis pigmentosa. In the formula(1), A is a group (p1), (p2) or (p3); R 1 is H, alkyl, aralkyl or OH or its ester; R 2 is H or alkyl; R 3 is halogen, H, alkyl or OH or its ester; R 4 is halogen, H, OH, alkoxy, amino, alkylamino or cycloalkylamino, R 3 and R 4 may be joined to each other through N to form an unsaturated [1,2,4]oxadiazine ring; R 5 is H, alkyl or cycloalkyl; m is 0 or 1; and n is 0 or 1. |
priorityDate | 2008-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.