http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2352531-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a5c7da3f772dfc46816ed110298c011 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
| filingDate | 2009-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75ead5907d6583833742c341b438e589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f81b6619edc0d8a784597b7af9846a8 |
| publicationDate | 2011-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2352531-A2 |
| titleOfInvention | Drug delivery implants and processes for their preparation |
| abstract | The invention discloses an implant suitable for delivery of at least one drug, the implant comprising a fibrillar collagen matrix having, as measured in Example 1, a viscosity of greater than 100 mPas, optionally greater than 103 mPas, further optionally greater than 106 mPas, still further optionally greater than 109 mPas when a collagen dispersion formed from 140 mg of the fibrillar collagen matrix is dispersed in 25 ml of 2mM HCl at a pH of less than 3.5 and at a temperature of 30.0 +/- 0.5°C. The invention also discloses a process for preparing an implant suitable for delivery of at least one drug, the process comprising the steps of forming a fibrillar collagen matrix from a collagen suspension; and carrying out a crosslinking step on either the fibrillar collagen matrix or the collagen suspension under conditions such that the fibrillar collagen matrix has, as measured in Example 1, a viscosity of greater than 100 mPas, optionally greater than 103 mPas, further optionally greater than 106 mPas, still further optionally greater than 109 mPas, when a collagen dispersion formed from 140 mg of the fibrillar collagen matrix is dispersed in 25 ml of 2mM HCl at a pH of less than 3.5 and at a temperature of 30.0 +/- 0.5°C. The invention further discloses use of the aforementioned fibrillar collagen matrix for the manufacture of the aforementioned implant for extended local delivery adjacent the site of implantation of at least one drug from the implant. |
| priorityDate | 2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.