Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ddb9f3656270bc5410be3679322fead |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6512 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6512 |
filingDate |
2009-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f187e44aa689acb025d9665c0bf9a7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5195f1e86fac4759f1c00bb3d3c3911 |
publicationDate |
2011-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2351762-A1 |
titleOfInvention |
NOVEL PYRIMIDINE DERIVATIVE AND METHOD FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR INTERMEDIATE |
abstract |
The problem to be solved of the present application is to provide a method for producing a novel pyrimidine derivative from an inexpensive compound which is industry-available with ease, and a method for producing an important intermediate of an HMG-CoA reductase inhibitor. The problem can be solved by, for example, reacting the compound (1) with the compound represented by (OR 1 ) 3P to obtain the phosphonate ester (3) and reacting the phosphonate ester (3) with the compound (4) in the presence of a base to obtain an HMG-CoA reductase inhibitor intermediate (5). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10377722-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3737676-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014203045-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278559-B2 |
priorityDate |
2008-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |