| abstract |
The invention relates to a process for the preparation of injectable pharmaceutical compositions containing a therapeutically and / or diagnostically active substance consisting of an active ingredient, a spacer molecule and at least one protein binding molecule and after contacting the body via the protein binding molecule covalently to body fluid or tissue components binds, so that a transport form of the active ingredient is present, which is pH-dependent, hydrolytic or enzymatic cleavable in the body with release of the active ingredient. |