http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2344889-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5dd388a5130b0bdede0fdfc6c2af6ed |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2009-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5962267240431e18c896d857c034c8c7 |
| publicationDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2344889-A2 |
| titleOfInvention | Methods for the selection of therapeutic treatments for cancer |
| abstract | Methods are disclosed for identifying subjects that would benefit from treatment with an inhibitor of HDAC6 deacetylase activity. The methods can include contacting a sample obtained from the subject with an of HDAC6 deacetylase activity detecting the amount of HDAC6 protein present in the tumor sample in comparison with a control. Such methods can be used to determine if a tumor in a subject is sensitive to treatment with an inhibitor of HDAC6 deacetylase activity. Also disclosed are methods for monitoring a response to a cancer treatment. Such methods are particularly useful in selecting a compound or multiple compounds for the treatment of cancer in a subject. Methods are also disclosed for identifying agents that inhibit cancer. The methods can include contacting at least one cell with a test agent and detecting an amount of HDAC6 protein in the cell in comparison to a control. |
| priorityDate | 2008-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 633.