| abstract |
Provided is a therapeutic agent for hyperparathyroidism, renal osteodystrophy, hypercalcemia and the like, which has a CaSR activating (agonist) action. A compound represented by the following general formula (1):n n[wherein, Ar which is a partial structure in the general formula (1) represents a phenyl group or a naphthyl group; R 1a and R 1b are the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; R 2a and R 2b are the same or different from each other, and represent a hydrogen atom, a halogeno group, or the like; A represents a single bond, an oxygen atom, or the like; B represents a single bond, a C1-C4 alkanediyl group, or the like; Z represents a carboxyl group or a tetrazolyl group; and m represents an integer of 1 to 3] or a pharmacologically acceptable salt thereof. |