http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2334816-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6115b7f4561db088f26a575e9339fed0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0a2b4d81f269b5ce61df24eb94136c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bdb35724ca45c25dce71bf5422117cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88491e02dc8971b62580ad18e441030b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86bf4086efc5a55ed3388c6d41b92c36 |
| publicationDate | 2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2334816-A1 |
| titleOfInvention | Genes associated with posttraumatic-stress disorder (ptsd) |
| abstract | The present invention relates to a method of identifying a predisposition for developing posttraumatic stress disorder (PTSD) in a subject comprising assessing in a sample obtained from said subject the expression level of one or more genes selected from the FK506 binding protein 5 (FKBP5) gene, the signal transducer and activator of transcription (STAT5B) gene and the nuclear factor I/A (NFIA) gene, wherein a decrease in the expression level of said one or more genes as compared to the expression level of the corresponding gene(s) of a control is indicative of a predisposition for developing PTSD. Further, the invention relates to a method of identifying a compound capable of preventing or treating PTSD or capable of serving as a lead compound for developing a compound capable of preventing or treating PTSD and also to a method of selecting a therapy to prevent or treat PTSD. |
| priorityDate | 2008-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.