| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b603ecd95b3b1497ae9f30752a676c0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5281b773800f0fca8ffff90b13980c66 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2009-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b78f81b05534690ecc024e020736ff5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c851875f554fcbd356112609fd4c3986
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1fdb188a03a4b5e07390ba75925b6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71adb85aedc2390ab7ff59fec636f92f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a4c7c9455f76c1c312a18de7fe272e |
| publicationDate |
2011-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2322658-A1 |
| titleOfInvention |
Signature for the diagnosis of breast cancer aggressiveness and genetic instability |
| abstract |
The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a breast cancer in a patient from a breast cancer sample of said patient, comprising: a) measuring in vitro the expression level of the POLQ gene and the expression level of a control gene in said patient breast cancer sample; b) calculating for said POLQ gene an expression level ratio of the expression level of POLQ to the expression of the said control gene in said patient breast cancer sample; c) comparing the said POLQ expression level ratio to a corresponding threshold value, and d) diagnosing breast cancer aggressiveness and genetic instability if the said POLQ expression level ratio is superior to a corresponding threshold values. Dedicated microarrays and kits are also described, as well as a method of selecting a suitable treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012156501-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790556-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015158729-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3365468-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020014297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3019821-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013102680-A1 |
| priorityDate |
2009-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |