http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2318823-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6e4a54a61ccf2f9cb4d46d5160eafe6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6413 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6484 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2009-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5067a392addf9576afc114e3a08f81c |
| publicationDate | 2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2318823-A1 |
| titleOfInvention | Methods and devices for assessment of mitochondrial function |
| abstract | Mitochondrial function is measured. Repetitive or continuous measurements are performed of prompt red fluorescence,emerging from the skin due to PpIX build up, and/or delayed fluorescence of PpIX. An estimateof the rate of PpIX generation is used as an indicator of mitochondrial integrity and ATP availability. Mitochondrial oxygen tension is determined from the delayed fluorescence lifetime of PpIX. When blood supply to the measurement volume is interrupted or reduced, the resulting changes to the mitochondrial oxygen tension allow an estimation of information about the kinetics of oxygen consumption in the mitochondria, such as the maximum rate of oxygen consumption as well as the Michaelis-Menten constant, providing information about the oxygen affinity of the mitochondrial respiratory chain. |
| priorityDate | 2008-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.