Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_488fd1e0383ac71e7f8cfb472ca2dc11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ac1f780d078521eac5cd33dc243fa8d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 |
filingDate |
2009-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e0f4b740429cf5baa42639d9ed5b68f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cf05bf7fb637d668507ce0111052c1f |
publicationDate |
2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2318515-A1 |
titleOfInvention |
Vaccines against clostridium difficile and methods of use |
abstract |
Attenuated microorganisms expressing Clostridium difficile antĪ¹gen(s), and methods of using the same for vaccination of patients are disclosed The invention provides an attenuated microorganism expressing an immunogenic portion of a C difficile Toxin A C-terminal repeat region and/or a C difficile Toxin B C-terminal repeat region The microorganism is an attenuated Salmonella comprising an integrated gene expression cassette that directs the expression of the immunogenic peptide from an in vivo inducible promoter. |
priorityDate |
2008-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |