| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_197d1066241480347ad3bd9386568c73 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 |
| filingDate |
2010-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51b755b8b6201a56b0306a49d79339e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3ecf47ea3184a929e99adc893f3e4fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e72e1699f321853a41d41f37fa050f4e |
| publicationDate |
2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2316931-A1 |
| titleOfInvention |
Polymer-coupled peptidases |
| abstract |
The invention relates to a simple method for modifying the specificity of peptidases of the hemostasis system, which by coupling polymers to the peptidases causes them to lose their reactivity in the hemostasis system, but still react with certain inhibitors, effectors and substrates. The invention further relates to methods for the detection or quantitative determination of inhibitors of peptidases in body fluids or other samples as well as methods for their neutralization and / or removal from liquids. Finally, the invention enables the use of polymer-coupled peptidases as drugs, and moreover provides a device that utilizes such peptidases to remove peptidase inhibitors from samples or from the bloodstream of a patient. |
| priorityDate |
2009-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |