http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2315761-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a695659dff59e19b48ff41f2a54442dc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2009-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21ce0a502bda3c402cba257180992b48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a03faa9af9ecf41d17cb9173ad7d740 |
| publicationDate | 2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2315761-A1 |
| titleOfInvention | Pharmaceutical compounds |
| abstract | The invention provides kinase inhibitor compounds of the formula (1): or salts, solvates, tautomers or N-oxides thereof; wherein X is O, CO, X 1 C(X 2 ), C(X 2 )X 1 , X 1 C(X 2 )X 1 , S, SO, SO 2 , NR c , SO 2 NR C or NR c SO 2 ; m is 0-2; n is 0-1; q is 0-2; A is C 1-6 alkylene optionally interrupted by O; R 1 is halogen, cyano, nitro, an optionally substituted acyclic C 1-6 hydrocarbon group, optionally substituted C 3-7 cycloalkyl, optionally substituted phenyl, optionally substituted five membered heteroaryl, NR 2 R 3 , R a -R b , O-R b or C(O)NR 2 R 8 ; R 4 is fluorine, chlorine, methyl or cyano; R 2 is hydrogen or optionally substituted C 1-4 alkyl; R 3 is R a -R b ; or NR 2 R 3 forms a 4 to 7 membered non-aromatic heterocyclic ring; Ra is a bond, C(X 2 ), C(X 2 )X 1 , SO, SO 2 or SO 2 NR c ; R b is hydrogen or an optionally substituted 3 to 7- membered carbocyclic or heterocyclic ring or an optionally substituted C 1-12 acyclic hydrocarbon group; R c is hydrogen or a C 1-4 hydrocarbon group; R d is O, CO, X 1 C(X 2 ), C(X 2 )X 1 , X 1 C(X 2 )X 1 , S, SO, SO 2 , NRC, SO 2 NR c or NR c SO 2 ; X 1 is O, S or NR c ; X 2 is =0, =S or =NR c ; but excluding the compound wherein m, n and q are all O, A is CH 2 and NR 2 R 3 is a 2-phenylmorpholin-4-yl group. |
| priorityDate | 2008-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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