| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_362d7df142655613551c77e74b6366de |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-18 |
| filingDate |
2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_246d4be83a9a9bdc3adee1cd347a70ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bee219fa1355c9557815feacff0ddad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e02287e47c07bcc233f04010ecd60a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50f8e8447b597aa110a37ff33a3281b8 |
| publicationDate |
2011-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2313379-A2 |
| titleOfInvention |
Process for the preparation of efavirenz |
| abstract |
A simple, cost-effective process for preparation of efavirenz of formula (I) comprising reacting a solution of 5-chloro-α-(cyclopropylethynyl)-2-amino-α-trifluoromethyl) benzene methanol of formula (II) in an organic solvent with triphosgene in the presence of an inorganic base at a temperature range -5 °C to 25 °C, adding water and isolating compound of formula (I). |
| priorityDate |
2008-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |