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filingDate 2009-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2011-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2308076-A2
titleOfInvention Glow discharge ion source
abstract A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode (14) located within an isolation valve (15) which is provided in the vacuum chamber. Reagent vapour may be provided through the tubular electrode (14) which is then subsequently ionised by the glow discharge. The resulting reagent ions may be used for Electron Transfer Dissociation of analyte ions generated by an atmospheric pressure ion source. Other embodiments are contemplated wherein the ions generated by the glow discharge device may be used to reduce the charge state of analyte ions by Proton Transfer Reaction or may act as lock mass or reference ions.
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