abstract |
An immune composition containing Globo H or its fragment (e.g., SSEA3) and an adjuvant, e.g., α -GalCer, for eliciting immune responses against Globo H or its fragment and uses thereof in cancer treatment. Also disclosed is a method of treating cancer by inhibiting the activity of one of FUT1 and FUT2 , both of which involve in Globo H biosynthesis. |