| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68e2664ac59d776440ad4a2707aa3a88 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-24 |
| filingDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_554caa3e1a1bf8c60281409ad97440c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e5f00900398951abade494dbdd7ca09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c9182809a7b240e759fbf28c30eaf91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566c3331b1a4f81a2c5c2fe5c973bb5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b0f8750a7088a2df6c694683a46d695 |
| publicationDate |
2011-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2301943-A1 |
| titleOfInvention |
Crystallization of epidaunorubicin x HCI |
| abstract |
The present invention relates to a form of crystalline epidaunorubicin hydrochloride which is stable and readily soluble, and to a process for the production thereof. This process comprises crystallizing epidaunorubicin hydrochloride in a solvent system including (a) solvent A which is selected from the group consisting of C1 and C2 halogenated solvents and mixtures thereof, (b) solvent B which is selected from the group consisting of C1 - C5 straight and branched alcohols and mixtures thereof, and (c)solvent C which is selected from the group consisting of C1 - C5 straight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to epidaunorubicin hydrochloride than solvent B. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10081652-B2 |
| priorityDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |