Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8885c3531c777418fd9c0ec1b457534d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ad5cd3c4e60ef3e67d60da396180cbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_527cbadc3d8cf81b5bf931c0dd99b3c1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-036 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-625 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
2009-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d24fa17d8f5b961775a5bc037d0e085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c9995ef566355898a6ca8589b306f53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_449ce1a422d5833677cec30ea5f49720 |
publicationDate |
2011-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2295565-A1 |
titleOfInvention |
Polynucleotide for releasing recombinant protein to the outside of eukaryotic cell |
abstract |
This invention provides a method for efficiently producing a recombinant protein by allowing the recombinant protein to express in a eukaryotic cell and releasing the expressed recombinant protein to the outside of the cell. The invention provides a polynucleotide used for producing a recombinant protein in a host cell comprising a polynucleotide encoding a glycosylation sequence comprising a transitional endoplasmic reticulum signal sequence and the sequence represented by: Asn-X- (Thr/Ser) (wherein X is an amino acid other than proline) and a polynucleotide encoding a target protein, which would not be efficiently released to the outside of the cell even when a transitional endoplasmic reticulum signal sequence is fused. The polynucleotide releases the target protein to the outside of the host cell via sugar chain modification. |
priorityDate |
2008-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |