| abstract |
In vitro methods for the determination of proenkephalin fragments in blood, plasma or CSF for diagnostic purposes, wherein proenkephalin fragments consisting of or comprising (i) the amino acids of ENK-fp consisting of amino acids 119 to 159 of the complete amino acid sequence of proenkephalin according to SEQ ID NO:1 and, optionally, (ii) additional amino acids of the proenkephalin sequence SEQ ID NO:1 downstream of said fragment are determined by an immunodiagnostic method using at least one antibody specifically binding to said proenkephalin fragment ENK-fp. |