http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2291075-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b944100daf03103e6704d7474fd127 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5758 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2009-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_394e8b93704815c08b8dce51624976dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8793e6319adb328d35dcb34993e823e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8822357eb760f3aa369d9fa6837803a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9de4d371c56de666a06d7644b6f4d1c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef8443a54c79920b36f2f1949b5853be |
| publicationDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2291075-A2 |
| titleOfInvention | Gastrin releasing peptide compounds |
| abstract | Methods and compositions for diagnosing, staging disease, monitoring therapeutic effect of drugs and imaging a patient are provided, including radiopharmaceutical formulations. Compositions comprising Ga-AMBA complexed with a radioactive isotope are provided; as are methods of imaging Gastrin Releasing Peptide receptor (GRP-R) bearing tissue and methods of diagnosing or staging disease in patients suspected of having disease associated with aberrant GRP-R function. Further, methods of monitoring therapeutic effect of a drug targeted to a receptor that crosstalks with GRP-R are provided; as are methods of pre-dosing/co-dosing non-target tissues containing GRP-R. Particularly, methods of monitoring activity of receptors and receptor pathways in vivo/in vitro by using a ligand that binds to the GRP-R are provided; as are methods of measuring the activity of a receptor or group of receptors and their associated pathways that exhibit crosstalk with the GRP-R by using such a ligand which is also detectable by external means. |
| priorityDate | 2008-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1422.