| abstract |
The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III,n nwherein R, R 1 , and R' are as defined in the specification, or a salt thereof, and a compound of formula IVn nwherein R, R 1 , R 2 and R' are as defined in the specification, and processes of manufacturing these. |