Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68f2bd3d611c7a2a832128d8430d9193 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2009-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_861dd0c3205e7f5548217faa5a57d13e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_668052310e4b4bd1bbe7106f2ace70b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356adf67832afa9022a5572bfd067580 |
publicationDate |
2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2286242-A1 |
titleOfInvention |
Modulators of acetyl-coenzyme a acyltransferase 1 or 2 in the treatment of acne, of seborrhoeic dermatitis or of hyperseborrhoea |
abstract |
The invention relates to an in vitro method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, comprising the determination of the ability of a compound to modulate the expression or the activity of acetyl-coenzyme A acyltransferase 1 (ACAA1) or of acetyl-coenzyme A acyltransferase 2 (ACAA2), and also to the use of modulators of the expression or of the activity of either of these enzymes, for the treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea. The invention also relates to methods for the in vitro diagnosis of or in vitro prognosis for these pathologies. |
priorityDate |
2008-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |