http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2286237-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae079092f2e6b17a5c5110af960b6c4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2009-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f3beb08e992563a3369f3bceaa942fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6894472718c60c93e856157cc94fc434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb23954f3667465f1b61fb9dafa91105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_372f6ca2b2f2a40696fbff820056d699 |
| publicationDate | 2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2286237-A1 |
| titleOfInvention | Mass spectrometric analysis |
| abstract | A method for assaying for a target analyte, which method comprises: (a) providing a plurality of samples which may comprise the target analyle, wherein each sample is differentially labelled with a mass label or a combination of mass labels, wherein the mass labels are from a set of mass labels, wherein each mass label is an isobaric mass label comprising a mass spectrometrically distinct mass marker group, such that the samples can be distinguished by mass spectrometry; (b) mixing the plurality of labelled samples to produce an analysis mixture and introducing the analysis mixture into a mass spectrometer; (c) selecting ions having a first mass to charge ratio equivalent to an ion of the target analyte labelled with a specific number of mass labels; (d) fragmenting ions of the first mass to charge ratio into a plurality of fragment ions, wherein a proportion of the plurality of fragment ions comprise at least one intact mass label; (e) selecting ions of a second mass to charge ratio equivalent to an ion of a fragment of the target analyte comprising at least one intact mass label; (f) fragmenting ions of the second mass to charge ratio into a plurality of further fragment ions, wherein a proportion of the further fragment ions are ions of the mass marker groups; (g) producing a mass spectrum of the further fragment ions produced in step (f); and (h) determining from the mass spectrum the quantity of the target analyte in each sample. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016032319-A1 |
| priorityDate | 2008-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.