| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4afb8b01aa8de7e0b24a86713b23a18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5af24bfbb650ae2e7ddf95747271e81 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2009-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aef40b167122f4a455b5cd44f5bd0aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_482ed5f4958defd9c3542e9d5669bcb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb809428692005045b6e9a8583b77509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e732ee665b84024400581e2e758fdeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf50e457d2fb3b27704f927b593326fe |
| publicationDate |
2011-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2285977-A1 |
| titleOfInvention |
Sirt1 polymorphic variants and methods of use thereof |
| abstract |
Provided herein are Sirtl polymorphic variants having a substitution at amino acid residue 107 or nucleotide 373. In certain embodiments, the Sirt1 polypeptide variants have a L107P substitution and the nucleic acid variants have a T373C substitution. Genetic and/or biochemical testing may be performed to identify whether a patient carries one of the disclosed polymorphic variants. Based on the polymorphic variant the patient carries, a medical practitioner may administer an appropriate therapy, such as a sirtuin activator. |
| priorityDate |
2008-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |